The tobacco warehouse of Ioannis Anastasiadis, was the first to be built in the district of Santa Barbara and the first major tobacco shop in the city of Drama. It is a two - storey building, which covers a total area of 250m2. It is covered by a pitched tiled roof and its walls consist of white stone. Next to the tobacco warehouse there is the so called stone house, which has similar perimetric walls to the tobacco warehouse and it was used as the owner’s residence. The construction of the warehouse in this area was not accidental, since the springs of Santa Barbara ensured the humidity which was necessary for the storage and processing of tobacco. The tobacco warehouse of Ioannis Anastasiadis changed many uses since its construction. In 1943 it was occupied and looted by the Bulgarian army and after the liberation of the city in 1944 and until 1953 it worked as a dance learning centre. For the next six years (until 1958) it was used as a dry cleaner and after that, the owners used it